Drug Allergies Q & A
Many people have reactions to medications, but only 5-10% of these reactions are true allergies. In most cases, they have a drug sensitivity or a side effect.
If you have a true drug allergy, your immune system develops antibodies to the medication. Every time you take that medication, the immune system releases chemicals like histamines that cause an allergic reaction.
You can have allergies to any type of medication, but drugs that frequently cause this problem include:
- Antibiotics such as penicillin
- Anti-seizure drugs
- ACE inhibitors
- Monoclonal antibodies
- Chemotherapy medications
- Nonsteroidal anti-inflammatory drugs
If you’re already allergic to one drug, you have a higher risk of developing an allergy to another unrelated drug.
An allergic reaction typically occurs within minutes to a few hours of taking the drug, although it’s also possible to have a delayed response. Since drugs get into your bloodstream, they can cause a wide range of allergy symptoms, including:
- Hives
- Coughing
- Sneezing
- Runny or congested nose
- Itchy, watery eyes
- Nausea and vomiting
- Diarrhea
- Headaches
Drug allergies can also cause a life-threatening anaphylactic reaction. Signs of anaphylaxis include shortness of breath, throat and mouth swelling, and dizziness or fainting. If you experience these symptoms, call 9-1-1 for immediate medical care.
After reviewing your history, Dr. Herrscher may perform a skin prick allergy test, which can identify an allergy in 15-20 minutes. Should the team have any doubts about your skin test, they may do a blood test or a graded challenge to verify the results.
During a graded challenge, you’ll take the drug in several doses, starting with a very small dose and gradually increasing each one to see if you have an allergic reaction.
Discontinuing the medication is the first step of treatment. For most patients, this puts an end to their drug allergy. However, if you’re allergic to a medication you need to take, Dr. Herrscher may recommend a treatment called drug desensitization.
During this treatment, you take progressively larger doses of the drug every 15-30 minutes over several hours or days. If this ongoing exposure to the drug desensitizes your immune system, you can keep taking the drug.
If you suspect you have a drug allergy, call AIR Care.
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